Hiv Infection Chronic Hepatitis B Virus (Hbv) Infection
Medicince introduction including background, function, caution, etc.
Indication It is indicated for the treatment of Chronic Hepatitis B virus infection in adults with compensated liver disease.
Side effects
Sever Acute Exacerbation of Hepatitis B New Onset or Worsening of Renal Impairment Common side effects include Headache, Abdominal pain, Fatigue, Cough, Nausea, Back pain. Mechanism of Action
Nucleotide reverse transcriptase inhibitor. Tenofovir alafenamide (TAF) is a phosphonoamidate prodrug of the nucleotide analog tenofovir (TFV). TAF is predominantly metabolized intracellularly to TFV. This intracellular metabolism is primarily catalyzed by cathepsin A (CatA).