Medicince introduction including background, function, caution, etc.
Indication For the management of the nasal symptoms of seasonal and perennial allergic and non-allergic rhinitis in adults, adolescents, and paediatric patients, 4 years of age and older.
Safety and effectiveness of fluticasone propionate aqueous nasal spray in children below 4 years of age have not been adequately established.
Side effects skin rash, oedema of the face and tongue, pruritus, urticaria
Mechanisam of Action The precise mechanism through which fluticasone propionate affects allergic rhinitis symptoms is not known. Corticosteroids have been shown to have a wide range of effects on multiple cell types (e.g., mast cells, eosinophils, neutrophils, macrophages, and lymphocytes) and mediators (e.g., histamine, eicosanoids, leukotrienes, and cytokines) involved in inflammation.