Patent medicine name
Xtandi 40 mg 120s
Manufacturer
Astellas
Specification
Physical Form: Capsule, Quantity: 120 /box, Storage: Room Temperature(10-30°C)
Price
$12,500-12800
Generic medicine name & Manufacturer
BDenza 40mg 112S, BDR Pharmaceuticals
Enzamide 40 mg, Intas
Specification
Physical Form: Capsule, Quantity: 112 /box, Storage: Room Temperature(10-30°C)
Price
$655-660
Composition
Enzalutamide (40mg)
Use
It is indicated for the treatment of patients with metastatic castration-resistant prostate cancer who have previously received docetaxel.
Medicince introduction including background, function, caution, etc.
Indication
For the treatment of patients with:
castration-resistant prostate cancer (CRPC)
metastatic castration-sensitive prostate cancer (mCSPC).
Side Effects
Back pain, diarrhea, arthralgia, hot flush, peripheral edema, musculoskeletal paindiscolouration.
Mechanism Of Action
It is a potent, competitive binder of androgens at the level of the AR. It prevents the translocation of the AR from the cytoplasm to the nucleus. Within the nucleus, it inhibits AR binding to chromosomal DNA, which prevents further transcription of tumor genes.
Use in Other language
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