It is a kinase inhibitor indicated for the treatment of patients with unresectable or metastatic melanoma with BRAF V600E mutation.
Medicince introduction including background, function, caution, etc.
Indication Vemurafenib is indicated in monotherapy for the treatment of adult patients with BRAF V600 mutation-positive unresectable or metastatic melanom
Sideeffects Increased sensitivity of your eyes to light, hair loss,thickening skin,rough scaly patches on skin.
Mechanisam of Action Vemurafenib causes programmed cell death in melanoma cell lines. Vemurafenib interrupts the B-Raf/MEK step on the B-Raf/MEK/ERK pathway − if the B-Raf has the common V600E mutation.