Olanib is used for the returning treatment of some types of ovarian cancer in patients who have had platinum chemotherapy or a change in a gene called BRCA. Olanib is a potent oral poly(ADP-ribose) polymerase (PARP) inhibitor. Cancer cells rely on PARP to stay alive, including cancer cells which BRCA gene change, thus Olanib works to stop PARP from repairing DNA damage this results in the death of cancer cells.
Medicince introduction including background, function, caution, etc.
Indication Olanib is used in the treatment of ovarian cancer that has returned after treatment using platinum chemotherapy
Sideeffects Loss of appetite,DIzziness,Headache,Indigestion
Mechanisam of Action Olanib is a potent oral poly(ADP-ribose) polymerase (PARP) inhibitor. PARP is a protein that helps cells repair themselves. By inhibiting the action of PARP cancer cells are unable to repair themselves.