Patent medicine name
Entresto 45/51 mg 60s
Manufacturer
Novartis
Specification
Physical Form: Tablet, Quantity: 60/bottle, Storage: Room Temperature(10-30°C)
Price
$600-620
Generic medicine name & Manufacturer
Vymada 100mg 28 Tablet,Novartis India Ltd
Specification
Physical Form: Tablet, Quantity: 28/box, Storage: Room Temperature(10-30°C)
Price
$60-70
Composition
Sacubitril+Valsartan
Use
It is an angiotensin II receptor blocker indicated to treat chronic heart failure, found to reduce the risk of cardiovascular death and hospitalisation related to heart failure.
Medicince introduction including background, function, caution, etc.
Indication
It is indicated to reduce the risk of cardiovascular death and hospitalization for heart failure in adult patients with chronic heart failure. Benefits are most clearly evident in patients with left ventricular ejection fraction (LVEF) below normal.
Side Effects
low blood pressure (hypotension),
high blood potassium (hyperkalemia),
cough,dizziness
Mechanism Of Action
It contains a neprilysin inhibitor, sacubitril, and an angiotensin receptor blocker, valsartan. ENTRESTO inhibits neprilysin (neutral endopeptidase; NEP) via LBQ657, the active metabolite of the prodrug sacubitril, and blocks the angiotensin II type-1 (AT1) receptor via valsartan
Use in Other language
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