Mercaptopurine is used in combination with other medicines as maintenance treatment of acute lymphoblastic leukemia. It belongs to the group of medicines known as antimetabolites
Medicince introduction including background, function, caution, etc.
Indication Mercaptopurine is an antineoplastic agent used to treat acute lymphocytic leukemia.
SideEffects Rash, itchy skin. stomach pain or tenderness. swelling of the feet
Mechanism Of Action Mercaptopurine (6-MP) competes with hypoxanthine and guanine for the enzyme hypoxanthine- guanine phosphoribosyltransferase (HGPRTase) and is itself converted to thioinosinic acid (TIMP).