It is used to treat cancer of the blood (chronic myeloid leukaemia and acute lymphocytic leukaemia) and gastrointestinal stromal tumour.
Medicince introduction including background, function, caution, etc.
Indication Chronic myeloid leukaemia Philadelphia chromosome positive acute lymphoblastic leukaemia Myelodysplastic/myeloproliferative diseases Hypereosinophilic syndrome (HES) and/or chronic eosinophilic leukaemia Gastrointestinal stromal tumours Dermatofibrosarcoma protuberanss. Side Effects Edema, nausea, vomiting, muscle cramps Mechanism Of Action Imatinib mesylate is a protein-tyrosine kinase inhibitor that inhibits the bcr-abl tyrosine kinase, the constitutive abnormal tyrosine kinase created by the Philadelphia chromosome abnormality in chronic myeloid leukemia