Patent medicine name
Palbace 125mg 21 s
Manufacturer
Pfizer Limited
Specification
Physical Form: Capsule, Quantity: 21/box, Storage: Room Temperature(10-30°C)
Price
$1560-1562
Generic medicine name & Manufacturer
Palbocent 125mg 21s, Incepta
Palbonix 125mg 30 Tablet ,Beacon
Specification
Physical Form: Capsule, Quantity: 21/box, Storage: Room Temperature(10-30°C)
Price
$295-300
Composition
Palbociclib (125mg)
Use
Palbociclib is used in combination with letrozole (an aromatase inhibitor) to treat postmenopausal women with estrogen receptor (ER) positive, HER2 negative advanced breast cancer.
Medicince introduction including background, function, caution, etc.
Indication
Palbociclib is a kinase inhibitor indicated for the treatment of hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced or metastatic breast cancer in combination with:
An aromatase inhibitor as initial endocrine based therapy in postmenopausal women; or
Fulvestrant in women with disease progression following endocrine therapy.
Side effects
Tiredness, weakness, hair loss, mouth sores
Mechanism of Action
Cyclin dependent kinases (CDK) 4,6 inhibitor
Reduces cellular proliferation of ER-positive breast cancer cell lines by blocking progression of the cell from G1 into S phase of the cell cycle
Use in Other language
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