Patent medicine name
Sandimmun Neoral 25mg 100 Capsule
Manufacturer
Specification
Physical Form: Capsule, Quantity: 100/box, Storage: Room Temperature(10-30°C)
Price
$30-40
Generic medicine name & Manufacturer
Specification
Price
Composition
Cyclosporine
Use
It is approved for a variety of conditions. Firstly, it is approved for the prophylaxis of organ rejection in allogeneic kidney, liver, and heart transplants. It is also used to prevent bone marrow transplant rejection. For the above indications, cyclosporine can be used in conjunction with azathioprine and corticosteroids. Finally, cyclosporine can be used in patients who have chronic transplant rejection and have received previous immunosuppressive therapy and to prevent or treat graft-versus-host disease.
Medicince introduction including background, function, caution, etc.
Indication
It is an immunosuppressant used to prevent organ rejection after a kidney, liver, or heart transplant. Neoral is also used to treat severe psoriasis or severe rheumatoid arthritis.
Side Effects
Unusual growth of body hair, nausea/vomiting, diarrhea, stomach upset
Mechanism Of Action
Its binding to the receptor cyclophilin-1 inside cells produces a complex known as cyclosporine-cyclophilin. This complex subsequently inhibits calcineurin, which in turn stops the dephosphorylation as well as the activation of the nuclear factor of activated T cells (NF-AT) that normally cause inflammatory reactions.
Use in Other language
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