Patent medicine name
Xovoltib 40mg Tablet
Manufacturer
Boehringer Ingelheim
Specification
Physical Form: Tablet, Quantity: 28 pill (7*4)/box, Storage: Room Temperature(10-30°C)
Price
$900-950
Generic medicine name & Manufacturer
Afanix 40mg 30 Tablet, Beacon Pharmaceuticals Limited
Specification
Physical Form: Tablet, Quantity: 30 pill/box, Storage: Room Temperature(10-30°C)
Price
$400-450
Composition
Afatinib dimaleate (40mg)
Use
Afatinib is used to treat non-small cell lung cancer (NSCLC) that is metastatic (spread to other parts of your body besides your lungs), and
has abnormal epidermal growth factor (EGF) receptor genes. These abnormal genes promote the growth of cancer cells.
Medicince introduction including background, function, caution, etc.
Indication
For the treatment of locally advanced or metastatic non-small cell lung cancer (NSCLC) with Epidermal Growth factor Receptor EGFR mutation.
For the treatment of locally advanced or metastatic NSCLC of squamous histology progressing on or after platinum based chemotherapy.
SideEffects
Acne, nose bleed, runny nose, nausea/vomiting, or loss of appetite
Mechanism Of Action
Afatinib is a potent and selective, irreversible ErbB family blocker . Afatinib covalently binds to and irreversibly blocks signaling from all homo and heterodimers formed by the ErbB family members EGFR (ErbB1), HER2 (ErbB2), ErbB3 and ErbB4
Use in Other language
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